A new process for customized patient-specific aortic stent graft using 3D printing technique. (March 2020)

• Record Type: Journal Article
• Authors: Lei, Yang; Chen, Xin; Li, Zhen; Zhang, Lei; Sun, Wei; Li, Lei; Tang, Feng
• Is Part Of: Medical engineering & physics. Volume 77(2020)
• Page Start: 80
• Page End: 87
• Publication Date: 2020-03
• Subjects: 3D printing -- Aortic dissection -- Personalized aortic stent graft -- Rapid prototyping sacrificial core-coating forming technique; EVAR endovascular aneurysm repair -- RPSC-CF "rapid prototyping" and "sacrificial core" and "coating" forming -- PET polyethylene terephthalate -- e-PTFE expanded polyethylene terephthalate -- Ni-Ti alloy nitinol -- CT computed tomography -- PU polyurethane -- FDA The Food and Drug Administration -- Af austenite-transition temperature -- PVA polyvinyl alcohol -- HG-stained histologicalgrading-stained; Biomedical engineering -- Periodicals; Biomedical Engineering -- Periodicals; Physics -- Periodicals; Génie biomédical -- Périodiques; Biomedical engineering; Electronic journals; Periodicals; 610.28
• DOI: 10.1016/j.medengphy.2019.12.002
• Languages: English
• ISSNs: 1350-4533

Abstract

Highlights: A new fabrication method for personalized stent graft based on 3D printing technology is proposed. The stent graft is made up of PU film and nitinol stent. Stent performance matches the invasive surgery requirements. The fabrication of a personalized stent graft can be achieved in 3-4 days. Abstract: Endovascular aneurysm repair (EVAR) is a popular and effective treatment for descending aortic disease. However, the majority of existing coating stents used in EVAR are of a standard design which may not meet the size or structural requirements of different patients. Therefore, in this paper, we propose using 3D printing and controlled deposition as a patient-specific aortic stent graft manufacturing technique. The methodology involves the use of a rapid prototyping study sacrificial core-coating forming (RPSC-CF) technique to develop an aortic stent graft that consists of a film and metallic stent. Polyether polyurethane and nickel-titanium alloys were chosen due to their shape memory properties and good biocompatibility. The resulting customized stent grafts meet the demands of personalized therapy and invasive surgery, and perform well as demonstrated from burst pressure testing and the degree of radial support provided and radial support force tests, laying the foundation for precise aortic dissection treatment.