Transient lupus anticoagulant: an unusual cause of bruising in children. Issue 5 (3rd September 2003)

• Record Type: Journal Article
• Authors: Anderson, A-K; Mohan, U; Liesner, R
• Is Part Of: Emergency medicine journal. Volume 20:Issue 5(2003)
• Page Start: e6
• Page End: e6
• Publication Date: 2003-09-03
• Subjects: lupus anticoagulant -- coagulation -- bleeding diathesis; aPTT, activated partial thromboplastin time -- LA, lupus anticoagulant -- APA, antiphospholipid antibody; Emergency medicine -- Periodicals; 616.02505
• DOI: 10.1136/emj.20.5.e6
• Languages: English
• ISSNs: 1472-0205

Abstract

Abstract : A child presented with excessive bruising and prolonged activated partial thromboplastin time. Mixing studies in plasma were positive for phospholipid dependence of the anticoagulant, confirming a diagnosis of lupus anticoagulant. Factor II level was reduced. Laboratory findings normalised after three months, with spontaneous resolution of bruising. This case demonstrates a transient antiphospholipid antibody syndrome as a rare presentation of bleeding diathesis in a previously healthy child, and should be considered in children with new onset bruising and prolonged activated partial thromboplastin time.