An assessment of techniques suitable for the diagnosis of sickle-cell disease and haemoglobin C disease in cord blood samples. Issue 6 (September 1970)

• Record Type: Journal Article
• Authors: Yawson, G. I.; Huntsman, R. G.; Metters, J. S.
• Is Part Of: Journal of clinical pathology. Volume 23:Issue 6(1970)
• Page Start: 533
• Page End: 537
• Publication Date: 1970-09
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.23.6.533
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Agar gel, cellulose acetate, and starch gel electrophoresis are all capable of diagnosing sickle-cell anaemia, sickle-cell haemoglobin C disease, and haemoglobin C disease in cord blood samples. Of these three electrophoretic techniques, agar gel is the easiest to interpret. Paper electrophoresis can reliably and rapidly detect sickle haemoglobin and haemoglobin C in cord blood samples. Being incapable of differentiating foetal and normal adult haemoglobin, the value of paper electrophoresis is limited to an initial screening procedure.