A method for the determination of free 131I in radio-iodinated lipids. Issue 1 (January 1962)

• Record Type: Journal Article
• Authors: Cox, A. G.; Hinchliffe, Zena
• Is Part Of: Journal of clinical pathology. Volume 15:Issue 1(1962)
• Page Start: 76
• Page End: 81
• Publication Date: 1962-01
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.15.1.76
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Experiments are described showing that an anion exchange resin may be used as a simple means of determining the amount of free radio-activity in emulsions of triolein and oleic acid labelled with 131 I in the form of 131 ICl. In the case of radio-iodinated triolein no special modifications are necessary. With radio-iodinated oleic acid, the working solution is made up with an excess of unlabelled oleic acid emulsion to prevent uptake of bound radio-activity by the resin. Recovery experiments show the method to be approximately 90% efficient, which is adequate when the radio-lipids are to be used for clinical purposes.