THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors. (11th November 2019)

• Record Type: Journal Article
• Authors: Alexander, Stephen P H; Christopoulos, Arthur; Davenport, Anthony P; Kelly, Eamonn; Mathie, Alistair; Peters, John A; Veale, Emma L; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Pawson, Adam J; Sharman, Joanna L; Southan, Christopher; Davies, Jamie A
• Other Names: Abbracchio Maria P investigator.; Alexander Wayne investigator.; Al-hosaini Khaled investigator.; Bäck Magnus investigator.; Beaulieu Jean‐Martin investigator.; Bernstein Kenneth E. investigator.; Bettler Bernhard investigator.; Birdsall Nigel JM investigator.; Blaho Victoria investigator.; Bousquet Corinne investigator.; Bräuner-Osborne Hans investigator.; Burnstock Geoffrey investigator.; Caló Girolamo investigator.; Castaño Justo P investigator.; Catt Kevin J investigator.; Ceruti Stefania investigator.; Chazot Paul investigator.; Chiang Nan investigator.; Chun Jerold investigator.; Cianciulli Antonia investigator.; Clapp Lucie H investigator.; Couture Réjean investigator.; Csaba Zsolt investigator.; Dent Gordon investigator.; Singh Khuraijam Dhanachandra investigator.; Douglas Steven D investigator.; Dournaud Pascal investigator.; Eguchi Satoru investigator.; Escher Emanuel investigator.; Filardo Edward investigator.; Fong Tung M investigator.; Fumagalli Marta investigator.; Gainetdinov Raul R investigator.; Gasparo Marc de investigator.; Gershengorn Marvin investigator.; Gobeil Fernand investigator.; Goodfriend Theodore L investigator.; Goudet Cyril investigator.; Gregory Karen J investigator.; Gundlach Andrew L investigator.; Hamann Jörg investigator.; Hanson Julien investigator.; Hauger Richard L investigator.; Hay Debbie investigator.; Heinemann Akos investigator.; Hollenberg Morley D investigator.; Holliday Nicholas D investigator.; Horiuchi Mastgugu investigator.; Hoyer Daniel investigator.; Hunyady László investigator.; Husain Ahsan investigator.; Ijzerman Adriaan P investigator.; Inagami Tadashi investigator.; Jacobson Kenneth A investigator.; Jensen Robert T investigator.; Jockers Ralf investigator.; Jonnalagadda Deepa investigator.; Karnik Sadashiva investigator.; Kaupmann Klemens investigator.; Kemp Jacqueline investigator.; Kennedy Charles investigator.; Kihara Yasuyuki investigator.; Kozielewicz Paweł investigator.; Kreienkamp Hans‐Jürgen investigator.; Kukkonen Jyrki P investigator.; Langenhan Tobias investigator.; Leach Katie investigator.; Lecca Davide investigator.; Lee John D investigator.; Leeman Susan E investigator.; Leprince Jérôme investigator.; Lolait Stephen J investigator.; Lupp Amelie investigator.; Macrae Robyn investigator.; Maguire Janet investigator.; Mazella Jean investigator.; McArdle Craig A investigator.; Melmed Shlomo investigator.; Michel Martin C investigator.; Miller Laurence investigator.; Mitolo Vincenzo investigator.; Mouillac Bernard investigator.; Murphy Philip M investigator.; Nahon Jean‐Louis investigator.; Norel Xavier investigator.; Nyimanu Duuamene investigator.; O'Carroll Anne‐Marie investigator.; Offermanns Stefan investigator.; Panaro Maria A investigator.; Pertwee Roger G investigator.; Pin Jean‐Philippe investigator.; Prossnitz Eric investigator.; Ramachandran Rithwik investigator.; Reinscheid Rainer K investigator.; Rondard Philippe investigator.; Rovati G Enrico investigator.; Ruzza Chiara investigator.; Sanger Gareth investigator.; Schöneberg Torsten investigator.; Schulte Gunnar investigator.; Schulz Stefan investigator.; Segaloff Deborah L investigator.; Serhan Charles N investigator.; Stoddart Leigh A investigator.; Sugimoto Yukihiko investigator.; Summers Roger investigator.; Tan Valerie investigator.; Thomas Walter investigator.; Timmermans Pieter BMWM investigator.; Tirupula Kalyan investigator.; Tulipano Giovanni investigator.; Unal Hamiyet investigator.; Unger Thomas investigator.; Vanderheyden Patrick investigator.; Vaudry David investigator.; Vaudry Hubert investigator.; Vilardaga Jean‐Pierre investigator.; Walker Christopher S investigator.; Ward Donald T investigator.; Wester Hans‐Jürgen investigator.; Willars Gary B investigator.; Williams Tom Lloyd investigator.; Woodruff Trent M investigator.; Yao Chengcan investigator.;
• Is Part Of: British journal of pharmacology. Volume 176(2019)Supplement 1
• Page Start: S21
• Page End: S141
• Publication Date: 2019-11-11
• Subjects: Pharmacology -- Periodicals; Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1111/bph.14748
• Languages: English
• ISSNs: 0007-1188

Abstract

Abstract : The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14748 . G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.