THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels. (11th November 2019)

• Record Type: Journal Article
• Authors: Alexander, Stephen P H; Mathie, Alistair; Peters, John A; Veale, Emma L; Striessnig, Jörg; Kelly, Eamonn; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Pawson, Adam J; Sharman, Joanna L; Southan, Christopher; Davies, Jamie A
• Other Names: Aldrich Richard W investigator.; Becirovic Elvir investigator.; Biel Martin investigator.; Catterall William A investigator.; Conner Alex C investigator.; Davies Paul investigator.; Delling Markus investigator.; Di Virgilio Francesco investigator.; Falzoni Simonetta investigator.; George Chandy investigator.; Goldstein Steve AN investigator.; Grissmer Stephan investigator.; Ha Kotdaji investigator.; Hammelmann Verena investigator.; Hanukoglu Israel investigator.; Jarvis Mike investigator.; Jensen Anders A investigator.; Kaczmarek Leonard K investigator.; Kellenberger Stephan investigator.; Kennedy Charles investigator.; King Brian investigator.; Lynch Joseph W investigator.; Perez-Reyes Edward investigator.; Plant Leigh D investigator.; Rash Lachlan D investigator.; Ren Dejian investigator.; Sivilotti Lucia G investigator.; Smart Trevor G investigator.; Snutch Terrance P investigator.; Tian Jinbin investigator.; Van den Eynde Charlotte investigator.; Vriens Joris investigator.; Wei Aguan D investigator.; Winn Brenda T investigator.; Wulff Heike investigator.; Xu Haoxing investigator.; Yue Lixia investigator.; Zhang Xiaoli investigator.; Zhu Michael investigator.;
• Is Part Of: British journal of pharmacology. Volume 176(2019)Supplement 1
• Page Start: S142
• Page End: S228
• Publication Date: 2019-11-11
• Subjects: Pharmacology -- Periodicals; Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1111/bph.14749
• Languages: English
• ISSNs: 0007-1188

Abstract

Abstract : The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14749 . Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.