The "pulvinar sign" in a case of paraneoplastic limbic encephalitis associated with non-Hodgkin's lymphoma. Issue 6 (16th May 2005)

• Record Type: Journal Article
• Authors: Mihara, M; Sugase, S; Konaka, K; Sugai, F; Sato, T; Yamamoto, Y; Hirota, S; Sakai, K; Sakoda, S
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 76:Issue 6(2005)
• Page Start: 882
• Page End: 884
• Publication Date: 2005-05-16
• Subjects: CSF, cerebrospinal fluid -- MRI, magnetic resonance imaging -- PLE, paraneoplastic limbic encephalitis -- vCJD, variant Creutzfeldt–Jakob disease; Creutzfeldt–Jakob disease -- paraneoplastic limbic encephalitis -- pulvinar sign; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.2004.049783
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : This paper reports a 59 year old woman with paraneoplastic limbic encephalitis associated with diffuse large B cell lymphoma. Her brain magnetic resonance imaging scan showed bilateral posterior thalamic hyperintensities, similar to the "pulvinar sign". Her symptoms included progressive psychiatric disturbance and resembled the initial symptoms of variant Creutzfeldt–Jakob disease (vCJD). Clinicians should consider this treatable disorder in the differential diagnosis of vCJD.