Uptake of dopamine and 5-hydroxytryptamine by platelets of patients with Parkinsonism. Issue 7 (July 1978)

• Record Type: Journal Article
• Authors: Aminoff, M J; Ehsanullah, R S; Turner, P
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 41:Issue 7(1978)
• Page Start: 589
• Page End: 592
• Publication Date: 1978-07
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.41.7.589
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : The uptake of tritiated dopamine and 5-hydroxytryptamine by platelets from 11 patients with Parkinsonism who were not receiving any medication, and from 11 control subjects matched for sex and for age within a decade was compared. No significant differences were found in the uptake of either amine. Our findings, therefore, provide no support for the belief that there is a generalised defect of dopamine systems in Parkinson's disease.