Associations of egg consumption with cardiovascular disease in a cohort study of 0.5 million Chinese adults. Issue 21 (21st May 2018)

• Record Type: Journal Article
• Authors: Qin, Chenxi; Lv, Jun; Guo, Yu; Bian, Zheng; Si, Jiahui; Yang, Ling; Chen, Yiping; Zhou, Yonglin; Zhang, Hao; Liu, Jianjun; Chen, Junshi; Chen, Zhengming; Yu, Canqing; Li, Liming
• Other Names: author non-byline.; Chen Junshi author non-byline.; Chen Zhengming author non-byline.; Clarke Robert author non-byline.; Collins Rory author non-byline.; Guo Yu author non-byline.; Li Liming author non-byline.; Lv Jun author non-byline.; Peto Richard author non-byline.; Walters Robin author non-byline.; Avery Daniel author non-byline.; Boxall Ruth author non-byline.; Bennett Derrick author non-byline.; Chang Yumei author non-byline.; Chen Yiping author non-byline.; Du Huaidong author non-byline.; Gilbert Simon author non-byline.; Hacker Alex author non-byline.; Hill Mike author non-byline.; Holmes Michael author non-byline.; Iona Andri author non-byline.; Kartsonaki Christiana author non-byline.; Kerosi Rene author non-byline.; Kong Ling author non-byline.; Kurmi Om author non-byline.; Lancaster Garry author non-byline.; Lewington Sarah author non-byline.; Lin Kuang author non-byline.; Mcdonnell John author non-byline.; Millwood Iona author non-byline.; Nie Qunhua author non-byline.; Radhakrishnan Jayakrishnan author non-byline.; Ryder Paul author non-byline.; Sansome Sam author non-byline.; Schmidt Dan author non-byline.; Sherliker Paul author non-byline.; Sohoni Rajani author non-byline.; Stevens Becky author non-byline.; Turnbull Iain author non-byline.; Walters Robin author non-byline.; Wang Jenny author non-byline.; Wang Lin author non-byline.; Wright Neil author non-byline.; Yang Ling author non-byline.; Yang Xiaoming author non-byline.; Bian Zheng author non-byline.; Guo Yu author non-byline.; Han Xiao author non-byline.; Hou Can author non-byline.; Pei Pei author non-byline.; Liu Chao author non-byline.; Jing Biao author non-byline.; Tan Yunlong author non-byline.; Yu Canqing author non-byline.; Pang Zengchang author non-byline.; Gao Ruqin author non-byline.; Li Shanpeng author non-byline.; Wang Shaojie author non-byline.; Liu Yongmei author non-byline.; Du Ranran author non-byline.; Zang Yajing author non-byline.; Cheng Liang author non-byline.; Tian Xiaocao author non-byline.; Zhang Hua author non-byline.; Zhai Yaoming author non-byline.; Ning Feng author non-byline.; Sun Xiaohui author non-byline.; Li Feifei author non-byline.; Lv Silu author non-byline.; Wang Junzheng author non-byline.; Hou Wei author non-byline.; Zeng Mingyuan author non-byline.; Jiang Ge author non-byline.; Zhou Xue author non-byline.; Yang Liqiu author non-byline.; He Hui author non-byline.; Yu Bo author non-byline.; Li Yanjie author non-byline.; Xu Qinai author non-byline.; Kang Quan author non-byline.; Guo Ziyan author non-byline.; Wang Dan author non-byline.; Hu Ximin author non-byline.; Wang Hongmei author non-byline.; Chen Jinyan author non-byline.; Fu Yan author non-byline.; Fu Zhenwang author non-byline.; Wang Xiaohuan author non-byline.; Weng Min author non-byline.; Guo Zhendong author non-byline.; Wu Shukuan author non-byline.; Li Yilei author non-byline.; Li Huimei author non-byline.; Fu Zhifang author non-byline.; Wu Ming author non-byline.; Zhou Yonglin author non-byline.; Zhou Jinyi author non-byline.; Tao Ran author non-byline.; Yang Jie author non-byline.; Su Jian author non-byline.; Liu Fang author non-byline.; Zhang Jun author non-byline.; Hu Yihe author non-byline.; Lu Yan author non-byline.; Ma Liangcai author non-byline.; Tang Aiyu author non-byline.; Zhang Shuo author non-byline.; Jin Jianrong author non-byline.; Liu Jingchao author non-byline.; Tang Zhenzhu author non-byline.; Chen Naying author non-byline.; Huang Ying author non-byline.; Li Mingqiang author non-byline.; Meng Jinhuai author non-byline.; Pan Rong author non-byline.; Jiang Qilian author non-byline.; Lan Jian author non-byline.; Liu Yun author non-byline.; Wei Liuping author non-byline.; Zhou Liyuan author non-byline.; Ping wang Ningyu Chen author non-byline.; Meng Fanwen author non-byline.; Qin Yulu author non-byline.; Wang Sisi author non-byline.; Wu Xianping author non-byline.; Zhang Ningmei author non-byline.; Chen Xiaofang author non-byline.; Zhou Weiwei author non-byline.; Luo Guojin author non-byline.; Li Jianguo author non-byline.; Chen Xiaofang author non-byline.; Zhong Xunfu author non-byline.; Liu Jiaqiu author non-byline.; Sun Qiang author non-byline.; Ge Pengfei author non-byline.; Ren Xiaolan author non-byline.; Dong Caixia author non-byline.; Zhang Hui author non-byline.; Mao Enke author non-byline.; Wang Xiaoping author non-byline.; Wang Tao author non-byline.; Zhang Xi author non-byline.; Zhang Ding author non-byline.; Zhou Gang author non-byline.; Feng Shixian author non-byline.; Chang Liang author non-byline.; Fan Lei author non-byline.; Gao Yulian author non-byline.; He Tianyou author non-byline.; Sun Huarong author non-byline.; He Pan author non-byline.; Hu Chen author non-byline.; Zhang Xukui author non-byline.; Wu Huifang author non-byline.; He Pan author non-byline.; Yu Min author non-byline.; Hu Ruying author non-byline.; Wang Hao author non-byline.; Qian Yijian author non-byline.; Wang Chunmei author non-byline.; Xie Kaixu author non-byline.; Chen Lingli author non-byline.; Zhang Yidan author non-byline.; Gu Dongxia Pan，qijun author non-byline.; Huang Yuelong author non-byline.; Chen Biyun author non-byline.; Yin Li author non-byline.; Liu Huilin author non-byline.; Fu Zhongxi author non-byline.; Xu Qiaohua author non-byline.; Xu Xin author non-byline.; Zhang Hao author non-byline.; Long Huajun author non-byline.; Li Xianzhi author non-byline.; Zhang Libo author non-byline.; Qiu Zhe author non-byline.;
• Is Part Of: Heart. Volume 104:Issue 21(2018)
• Page Start: 1756
• Page End: 1763
• Publication Date: 2018-05-21
• Subjects: egg consumption -- cardiovascular disease -- ischemic heart disease -- major coronary events -- hemorrhagic stroke -- ischemic stroke -- prospective study; Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/heartjnl-2017-312651
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Objective: To examine the associations between egg consumption and cardiovascular disease (CVD), ischaemic heart disease (IHD), major coronary events (MCE), haemorrhagic stroke as well as ischaemic stroke. Methods: During 2004–2008, over 0.5 million adults aged 30–79 years were recruited from 10 diverse survey sites in China. Participants were asked about the frequency of egg consumption and were followed up via linkages to multiple registries and active investigation. Among 461 213 participants free of prior cancer, CVD and diabetes, a total of 83 977 CVD incident cases and 9985 CVD deaths were documented, as well as 5103 MCE. Stratified Cox regression was performed to yield adjusted hazard ratios for CVD endpoints associated with egg consumption. Results: At baseline, 13.1% of participants reported daily consumption (usual amount 0.76 egg/day) and 9.1% reported never or very rare consumption (usual amount 0.29 egg/day). Compared with non-consumers, daily egg consumption was associated with lower risk of CVD (HR 0.89, 95% CI 0.87 to 0.92). Corresponding multivariate-adjusted HRs (95% CI) for IHD, MCE, haemorrhagic stroke and ischaemic stroke were 0.88 (0.84 to 0.93), 0.86 (0.76 to 0.97), 0.74 (0.67 to 0.82) and 0.90 (0.85 to 0.95), respectively. There were significant dose-response relationships of egg consumption with morbidity of all CVD endpoints (P for linear trend <0.05). Daily consumers also had an 18% lower risk of CVD death and a 28% lower risk of haemorrhagic stroke death compared to non-consumers. Conclusion: Among Chinese adults, a moderate level of egg consumption (up to <1 egg/day) was significantly associated with lower risk of CVD, largely independent of other risk factors.