CD10 positive thyroid marginal zone non-Hodgkin lymphoma. Issue 11 (1st November 1999)

• Record Type: Journal Article
• Authors: Millar, E K; Waldron, S; Spencer, A; Braye, S
• Is Part Of: Journal of clinical pathology. Volume 52:Issue 11(1999)
• Page Start: 849
• Page End: 850
• Publication Date: 1999-11-01
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.52.11.849
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.