Columnar cuff cancer after restorative proctocolectomy for familial adenomatous polyposis. Issue 5 (1st November 2000)

• Record Type: Journal Article
• Authors: Vuilleumier, H; Halkic, N; Ksontini, R; Gillet, M
• Is Part Of: Gut. Volume 47:Issue 5(2000)
• Page Start: 732
• Page End: 734
• Publication Date: 2000-11-01
• Subjects: familial adenomatous polyposis -- anastomosis -- adenocarcinoma; Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.47.5.732
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : AIMS: Restorative proctocolectomy with ileoanal anastomosis is one of the treatments of choice for patients suffering from familial adenomatous polyposis (FAP). However, any residual rectal mucosa left behind after mucosectomy is at risk for the development of neoplasia. CASE REPORT: A 31 year old male patient with FAP underwent restorative proctocolectomy with a pelvic ileal pouch-anal anastomosis. Seven years later he presented with right inguinal and perianal pain. A diagnosis of invasive columnar cuff carcinoma was made. DISCUSSION: Islets of columnar epithelium may be left behind after restorative proctocolectomy, exposing the patient to later malignant change. This risk must be emphasised and prevented by regular surveillance of the anastomosis.