Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration. Issue 4 (16th March 2006)

• Record Type: Journal Article
• Authors: Choi, K-D; Kim, J S; Park, S-H; Kim, Y K; Kim, S E; Smitt, P S
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 77:Issue 4(2006)
• Page Start: 525
• Page End: 528
• Publication Date: 2006-03-16
• Subjects: CSF, cerebrospinal fluids -- PCD, paraneoplastic cerebellar degeneration; cerebellar hypermetabolism -- FDG PET -- paraneoplastic cerebellar degeneration; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.2005.075325
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.