Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15). Issue 6 (June 1997)

• Record Type: Journal Article
• Authors: Stallings, R; Vaughn, D; Hall, K; Joyce, C; Ryan, F; Barton, D; Geraghty, M
• Is Part Of: Journal of medical genetics. Volume 34:Issue 6(1997)
• Page Start: 512
• Page End: 514
• Publication Date: 1997-06
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.34.6.512
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46, XX (50) and the karyotype from skin fibroblasts is 46, XX (28)/46, XX, der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discussed.