Advances in Chiral Metal–Organic and Covalent Organic Frameworks for Asymmetric Catalysis. Issue 22 (18th March 2021) - Zhang, Hao
Abstract: Asymmetric catalysis is of crucial importance owing to the huge and rising demand for optically pure substances. Metal–organic frameworks (MOFs) and covalent organic frameworks (COFs), as two emerging crystalline porous materials, have presented great promising applications for heterogeneous asymmetric catalysis. The unique properties, such as, highly regular porous structures, prominent structural tunability, and well‐ordered catalytic sites, render chiral MOFs (CMOFs) and chiral COFs (CCOFs) highly active and enantioselective for a large number of asymmetric catalytic organic transformations. Furthermore, they provide a useful platform for facile mechanistic understanding and catalyst design. This review provides an overview of the advancements in CMOFs and CCOFs for asymmetric catalysis. The designs, syntheses and structures of these crystalline porous materials, and their asymmetric catalytic performance are described. And the perspectives on challenges and opportunities in development of CMOFs and CCOFs are discussed. It is anticipated that this review will shed light on the heterogeneous asymmetric catalysis with CMOFs and CCOFs and motivate further research in this promising field. Abstract : Chiral metal–organic frameworks (MOFs) and covalent organic frameworks (COFs) represent attractive and promising heterogeneous asymmetric catalysts for a wide range of organic transformations. This review provides a comprehensive overview of the developments of asymmetric catalysis by chiral MOF and COF catalysts with emphasis on their syntheses, structures, and asymmetric catalytic performance.