Abnormal lactic dehydrogenase isoenzyme patterns in ulcerative colitis with precancerous change. Issue 1 (January 1971)

• Record Type: Journal Article
• Authors: Lewis, B.; Morson, B. C.; February, A. W.; Jones, J. Hywel; Misiewicz, J. J.
• Is Part Of: Gut. Volume 12:Issue 1(1971)
• Page Start: 16
• Page End: 19
• Publication Date: 1971-01
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.12.1.16
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : The isoenzyme pattern of lactic dehydrogenase was measured in rectal biopsies from six patients with ulcerative colitis in whom precancerous histological changes had been independently recognized. There was a highly significant increase in the ratio of isoenzymes IV + V to I + II. This suggests that lactic dehydrogenase isoenzyme measurement may prove a valuable addition to histology in the recognition of precancer in ulcerative colitis.