Quantitative assessment of aortic regurgitation following transcatheter aortic valve replacement. (3rd July 2021)

• Record Type: Journal Article
• Authors: Kitamura, Mitsunobu; Von Roeder, Maximilian; Abdel-Wahab, Mohamed
• Is Part Of: Expert review of cardiovascular therapy. Volume 19:Number 7(2021)
• Page Start: 633
• Page End: 645
• Publication Date: 2021-07-03
• Subjects: Aortic regurgitation -- paravalvular leak -- transcatheter aortic valve replacement -- multiparametric approach -- quantitative evaluation -- video-densitometric angiography; Cardiovascular agents -- Research -- Periodicals; 616.12061
• DOI: 10.1080/14779072.2021.1924675
• Languages: English
• ISSNs: 1477-9072

Abstract

ABSTRACT: Introduction : Transcatheter aortic valve replacement (TAVR) is expanding to lower risk and younger patients with severe symptomatic aortic valve disease. Despite clinical and technological improvements, post-procedural aortic regurgitation (AR) remains a limitation of TAVR, particularly when compared to surgical aortic valve replacement. Although several methods for AR quantification after TAVR are currently available, its exact graduation in everyday clinical practice remains challenging. Areas covered : This review describes the currently available evaluation methods of AR after TAVR, with a special emphasis on the quantitative assessment using videodensitometric angiography, echocardiography and cardiac magnetic resonance imaging. Expert opinion : In the majority of clinical scenarios, satisfactory evaluation of post-TAVR AR can be achieved with a combination of post-procedural angiography, hemodynamic indices and transthoracic echocardiography. Nevertheless, some TAVR patients show 'intermediate' forms of post-procedural AR, in which quantitative evaluation is mandatory for prognostic purposes and further decision-making. Notably, interpretation of quantitative measures early post-TAVR is challenging because of the lack of left ventricular enlargement. Video-densitometric angiography is an emerging method that appears to be clinically attractive for immediate post-TAVR assessment, but requires further validation in everyday clinical practice.