A new p-terphenyl derivative from the fruiting bodies of Sarcodon imbricatus (L.) P. Karst. Issue 15 (3rd August 2021)

• Record Type: Journal Article
• Authors: Zhang, Feng-Ming; Wang, Yue-Hu; Zhao, Ping; Yu, Fu-Qiang
• Is Part Of: Natural product research. Volume 35:Issue 15(2021)
• Page Start: 2482
• Page End: 2488
• Publication Date: 2021-08-03
• Subjects: Sarcodon imbricatus -- terphenyls -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1680664
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new p -terphenyl, 2', 3'-diacetoxy-4, 5, 5', 6', 4'', 5''-hexahydroxy- p -terphenyl (1 ), along with 12 known compounds were isolated from the fruiting bodies of Sarcodon imbricatus (Bankeraceae). Their structures were confirmed on the basis of extensive spectroscopic analysis and comparison with the spectral data in the literature. Compound 1 exhibited weak cytotoxicity against colon cancer SW480 and leukemia HL-60 cell lines, with IC50 values of 55.02 ± 1.79 μM and 44.71 ± 2.15 μM, respectively. Graphical Abstract: