Reversible regulation of metallo-base-pair interactions for DNA dehybridization by ultrasound. Issue 60 (7th July 2021)

• Record Type: Journal Article
• Authors: Huo, Shuaidong; Zhou, Yu; Liao, Zhihuan; Zhao, Pengkun; Zou, Miancheng; Göstl, Robert; Herrmann, Andreas
• Is Part Of: Chemical communications. Volume 57:Issue 60(2021)
• Page Start: 7438
• Page End: 7440
• Publication Date: 2021-07-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc02402g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Ultrasound leads to the reversible dissociation of DNA metallo-base-pairs when these motifs are functionalized with oligodeoxynucleotide sequences of sufficient length. Abstract : Mechanical force applied by ultrasound in solution leads to the dissociation of DNA metallo-base-pair interactions when these motifs are functionalized with oligodeoxynucleotide sequences of sufficient length. The annealing and force-induced denaturing process is followed by the attachment of distance-sensitive fluorescent probes and is found to be reversible.