Enzymuria in a population living near a cadmium battery plant. Issue 11 (November 1995)

• Record Type: Journal Article
• Authors: Järup, L; Carlsson, M D; Elinder, C G; Hellström, L; Persson, B; Schütz, A
• Is Part Of: Occupational and environmental medicine. Volume 52:Issue 11(1995)
• Page Start: 770
• Page End: 772
• Publication Date: 1995-11
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oem.52.11.770
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : OBJECTIVES--To study the body burden of cadmium and signs of tubular dysfunction in a rural population living near a closed nickel cadmium battery plant. METHODS--Cadmium and N-acetyl-beta-glucosaminidase (NAG) in urine were measured in 72 subjects who lived close to the plant. RESULTS--Residents living close to the plant had higher median urinary cadmium concentrations than those living farther away (1.01 v 0.46 nmol/mmol creatinine) and than a control group (0.2 nmol/mmol creatinine). There was a significant correlation between urinary cadmium and the excretion of NAG in urine as well as signs of tubular dysfunction in residents who excreted urinary cadmium above 0.5 nmol/mmol creatinine. CONCLUSION--Tubular dysfunction may appear in environmentally exposed subjects at lower cadmium body burdens than previously anticipated.