Anti-PL-7 antibody-positive dermatomyositis with progressive interstitial pneumonia complicated with tracheal ulcer. (2021)

• Record Type: Journal Article
• Authors: Sato, Shintaro; Yamakawa, Hideaki; Takemura, Tamiko; Nakamura, Tomohiko; Oba, Tomohiro; Nishizawa, Tomotaka; Kawabe, Rie; Akasaka, Keiichi; Amano, Masako; Matsushima, Hidekazu
• Is Part Of: Respiratory medicine case reports. Volume 33(2021)
• Publication Date: 2021
• Subjects: Dermatomyositis -- Idiopathic inflammatory myopathy -- Interstitial pneumonia -- Tracheal ulcer; ARS anti-aminoacyl tRNA synthetase -- DM dermatomyositis -- GGO ground-glass opacity -- IIM idiopathic inflammatory myopathy -- ILD interstitial lung disease -- MDA5 melanoma-differentiation-associated gene 5 -- PM polymyositis; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2021.101449
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: Tracheobronchial lesions are rare extramuscular complications for idiopathic inflammatory myopathies including dermatomyositis. We herein report a 65-year-old woman with tracheal ulcer during the progression of dermatomyositis-associated interstitial lung disease. Treatment with corticosteroids combined with immunosuppressive agents resulted in improvement of the tracheal ulcer and pulmonary involvement. We believe that the tracheal ulceration might reflect the disease behaviour of dermatomyositis and dermatomyositis-associated interstitial pneumonia.