Simultaneous presentation of sarcoidosis and acute myeloid leukaemia: predisposition to pulmonary haemorrhage. Issue 7 (July 1994)

• Record Type: Journal Article
• Authors: Williams, B; Francis, A; Durrant, S
• Is Part Of: Journal of clinical pathology. Volume 47:Issue 7(1994)
• Page Start: 672
• Page End: 673
• Publication Date: 1994-07
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.47.7.672
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A case of coexistent acute myeloid leukaemia and sarcoidosis is reported. This was complicated by recurrent pulmonary haemorrhage during reinduction and consolidation chemotherapy. A review of published papers on malignancy and sarcoidosis, in particular acute leukaemia is given. The outcome of most cases of acute leukaemia and sarcoidosis is poor with respiratory complications a frequent cause of death in this group. It is proposed that modifications to treatment to avoid pulmonary toxicity and maintenance of platelet counts above 40 x 10(9)/l are warranted to reduce the risk of this complication.