Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin's lymphoma. Issue 1 (January 1987)

• Record Type: Journal Article
• Authors: Smith, M E; Holgate, C S; Williamson, J M; Grigor, I; Quirke, P; Bird, C C
• Is Part Of: Journal of clinical pathology. Volume 40:Issue 1(1987)
• Page Start: 34
• Page End: 41
• Publication Date: 1987-01
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.40.1.34
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : An immunohistochemical study of 46 B and T cell non-Hodgkin's lymphomas, using monoclonal antibodies to the products of the major histocompatibility complex (MHC) class II antigen subregions, DP, DQ, and DR, showed that most B and T cell lymphomas express these antigens. Both coordinate and non-coordinate expression of MHC class II antigens was observed, but this did not correlate with immunological phenotype, morphological grade, or proliferation index as determined by flow cytometry.