Monoclonal antibodies to detect human tumours: an experimental approach. Issue 3 (March 1981)

• Record Type: Journal Article
• Authors: Moshakis, V; McIlhinney, R; Raghavan, D; Neville, A M
• Is Part Of: Journal of clinical pathology. Volume 34:Issue 3(1981)
• Page Start: 314
• Page End: 319
• Publication Date: 1981-03
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.34.3.314
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The use of monoclonal antibodies which can be raised to antigens of choice offers a selective and specific approach for the detection of tumours both in vivo and at a cellular level in biopsy specimens. We demonstrate that a monoclonal antibody raised to human teratoma will localise in a teratoma, growing as a xenograft in immune-suppressed mice.