Congenital microvillous atrophy: specific diagnostic features. Issue 2 (February 1985)

• Record Type: Journal Article
• Authors: Phillips, A D; Jenkins, P; Raafat, F; Walker-Smith, J A
• Is Part Of: Archives of disease in childhood. Volume 60:Issue 2(1985)
• Page Start: 135
• Page End: 140
• Publication Date: 1985-02
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.60.2.135
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Proximal small intestinal and colonoscopic mucosal biopsies from two children with the intractable diarrhea of infancy syndrome were examined by electron microscopy. Microvillous involutions were found in the small and large bowel of both patients. We suggest that this is a specific diagnostic finding for congenital microvillous atrophy, a distinct disorder within the intractable diarrhoea syndrome which has an extremely poor prognosis.