Disseminated pneumocystis carinii infection in AIDS. Issue 10 (October 1991)

• Record Type: Journal Article
• Authors: Coker, R J; Clark, D; Claydon, E L; Gompels, M; Ainsworth, J G; Lucas, S B; Miller, R; Goldin, R D; Pinching, A J; Harris, J R
• Is Part Of: Journal of clinical pathology. Volume 44:Issue 10(1991)
• Page Start: 820
• Page End: 823
• Publication Date: 1991-10
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.44.10.820
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis against P carinii pneumonia was ineffective at suppressing dissemination. The knowledge that extrapulmonary infection can occur has implications for the detection and treatment of, and prophylaxis against, P carinii infection. The survival of patients with disseminated pneumocystosis is particularly poor, and may be due to a lack of clinical awareness and consequent delay in diagnosis.