Work participation in spondyloarthritis across countries: analysis from the ASAS-COMOSPA study. Issue 9 (2nd June 2018)

• Record Type: Journal Article
• Authors: Rodrigues Manica, Santiago; Sepriano, Alexandre; Ramiro, Sofia; Pimentel Santos, Fernando; Putrik, Polina; Nikiphorou, Elena; Norton, Sam; Molto, Anna; Dougados, Maxime; van der Heijde, Désirée; Landewé, Robert B M; van den Bosch, Filip E; Boonen, Annelies
• Other Names: Allali Fadoua author non-byline.; González Raquel Almodovar author non-byline.; Blanco-Morales Elena Alonso author non-byline.; Alvarellos Alejandro author non-byline.; Espinar Maria Aparicio author non-byline.; Atagunduz Pamir author non-byline.; Bakker Pauline author non-byline.; Barreira Juan C author non-byline.; Benbrahim Leila author non-byline.; Benchekroun Bahia author non-byline.; Berman Alberto author non-byline.; Braun Juergen author non-byline.; Cantagrel Alain author non-byline.; Caporali Roberto author non-byline.; Carvalho Pedro author non-byline.; Casado Gustavo author non-byline.; Wei James Cheng-Chung author non-byline.; Colombres Francisco author non-byline.; Miguel Mendieta Eugenio Del author non-byline.; Diaz-Garcia Juan D author non-byline.; Bandt Michel De author non-byline.; Duarte Vanesa author non-byline.; Carballido Cristina Fernandez author non-byline.; Fernandez Espartero Mari Cruz author non-byline.; Fernandez-Prada Manuel author non-byline.; Flipo Rene-Marc author non-byline.; Ugalde Pilar Font author non-byline.; Gaudin Philippe author non-byline.; Goupille Philippe author non-byline.; Cánovas Dolors Grados author non-byline.; Masmitjá Jordi Gratacós author non-byline.; Grosso Vittorio author non-byline.; Ichikawa Naomi author non-byline.; Inoue Hisashi author non-byline.; Kaneko Yuko author non-byline.; Kawasaki Taku author non-byline.; Kobayashi Shigeto author non-byline.; Lahiri Manjari author non-byline.; Maldonado-Ficco Hernán author non-byline.; Marhadour M author non-byline.; Martínez Alejandro author non-byline.; Matsui Kazuo author non-byline.; Esteban Ramón Mazzuchelli author non-byline.; Micelli Corinne author non-byline.; Min Chisun author non-byline.; Morita Mitsuhiro author non-byline.; Mendoza Juan Mulero author non-byline.; Noguera Pons Jose Raul author non-byline.; Okada Masato author non-byline.; Ortiz Alberto author non-byline.; Packham Jon author non-byline.; Pendón Gisela author non-byline.; Pereira Dora author non-byline.; Pereira da Silva José A author non-byline.; Rkain Hanan author non-byline.; Rillo Oscar author non-byline.; Lozano Carlos Rodriguez author non-byline.; Ruyssen-Witrand Adeline author non-byline.; Salas Adrián author non-byline.; Salinas-Ramos Carlos author non-byline.; Santosa Amelia author non-byline.; Saraux Alain author non-byline.; Sengupta Raj author non-byline.; Siebert Stefan author non-byline.; Soubrier Martin author non-byline.; Spiegel Caroline author non-byline.; Stolwijk Carmen author non-byline.; Tada Kurisu author non-byline.; Takizawa Naoho author non-byline.; Taniguchi Yoshinori author non-byline.; Taniguchi Atsuo author non-byline.; Chou Chung Tei author non-byline.; Teoh Lay-Keng author non-byline.; Tomita Tetsuya author non-byline.; Tsai Wen-chan author non-byline.; Tsuji Shigeyoshi author non-byline.; Tsyplenkova Olga author non-byline.; Tubergen Astrid van author non-byline.; Vakil-Gilani Kiana author non-byline.; Valle-oñate Rafael author non-byline.; Varkas Gaelle author non-byline.; Villaverde Virginia author non-byline.; Yap Ai author non-byline.; Montejo Pedro Zarco author non-byline.;
• Is Part Of: Annals of the rheumatic diseases. Volume 77:Issue 9(2018)
• Page Start: 1303
• Page End: 1310
• Publication Date: 2018-06-02
• Subjects: spondyloarthritis -- economic evaluations -- epidemiology -- outcomes research; Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2018-213464
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Objectives: To explore the role of individual and country level socioeconomic (SE) factors on employment, absenteeism and presenteeism in patients with spondyloarthritis (SpA) across 22 countries worldwide. Methods: Patients with a clinical diagnosis of SpA fulfilling the ASAS classification criteria and in working age (≤65 years) from COMOSPA were included. Outcomes of interest were employment status, absenteeism and presenteeism, assessed by the Work Productivity and Activity Impairment Specific General Health questionnaire. Three multivariable models were built (one per outcome) using mixed-effects binomial (for work status) or ordinal regressions (for absenteeism and presenteeism), with country as random effect. The contribution of SE factors at the individual-level (eg, gender, education, marital status) and country-level (healthcare expenditure (HCE) per capita, Human Development Index (HDI) and gross domestic product per capita) SE factors, independent of clinical factors, was assessed. Results: In total, 3114 patients with SpA were included of which 1943 (62%) were employed. Physical function and comorbidities were related to all work outcomes in expected directions and disease activity also with absenteeism and presenteeism. Higher education (OR 4.2 (95% CI 3.1 to 5.6)) or living in a country with higher HCE (OR 2.3 (1.5 to 3.6)) or HDI (OR 1.9 (1.2 to 3.3)) was positively associated with being employed. Higher disease activity was associated with higher odds for absenteeism (OR 1.5 (1.3 to 1.7)) and presenteeism (OR 2.1 (1.8 to 2.4)). No significant association between individual-level and country-level SE factors and absenteeism or presenteeism was found. Conclusions: Higher education level and higher country SE welfare are associated with a higher likelihood of keeping patients with SpA employed. Absenteeism and presenteeism are only associated with clinical but not with individual-level or country-level SE factors.