Recurrent abducens nerve palsy and hypophosphatasia syndrome. Issue 4 (11th April 2019)

• Record Type: Journal Article
• Authors: Khade, Neha; Carrivick, Simon; Orr, Carolyn; Prentice, David
• Is Part Of: BMJ case reports. Volume 12:Issue 4(2019)
• Publication Date: 2019-04-11
• Subjects: cranial nerves -- calcium and bone -- metabolic disorders; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2018-226895
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 47-year-old woman presented with six episodes of horizontal binocular double vision over a 2-year period. CT imaging was significant for extensive dural calcification in the spine and calcification of the skull base, likely involving Dorello's canal. Biochemical testing revealed a persistently low alkaline phosphatase level. Recurrent nerve palsy may possibly be induced by mechanical compression of the sixth cranial nerve in Dorello's canal from calcification due to hypophosphatasia syndrome.