Immunoengineering: A Nanoparticle Platform for Improved Potency, Stability, and Adjuvanticity of Poly(I:C) (Adv. Therap. 1/2020). Issue 1 (9th January 2020)

• Record Type: Journal Article
• Authors: Gale, Emily C.; Roth, Gillie A.; Smith, Anton A. A.; Alcántara‐Hernández, Marcela; Idoyaga, Juliana; Appel, Eric A.
• Is Part Of: Advanced therapeutics. Volume 3:Issue 1(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-01-09
• Subjects: Therapeutics -- Periodicals; Pharmaceutical technology -- Periodicals; Pharmacogenetics -- Periodicals; 615.5
• DOI: 10.1002/adtp.202070001
• Languages: English
• ISSNs: 2366-3987

Abstract

Abstract : The image representing article number 1900174, by Eric A. Appel and co‐workers shows the activation of a dendritic cell, following uptake of adjuvant‐loaded nanoparticles. The manuscript reports the screening of a combinatorial library of polymers for the encapsulation of the adjuvant poly(I:C) to optimize adjuvant potency while minimizing toxicity.