AB0375 Success rates of assisted reproductive techniques in patients with inflammatory rheumatic disease. (23rd January 2014)

• Record Type: Journal Article
• Authors: Trujillo, E.; Padrόn, E.; Flores, M.; Viotti, J.M.; de la Rosa, C.; Bethencourt, J.J.; Bustabad, S.
• Is Part Of: Annals of the rheumatic diseases. Volume 71(2012)Supplement 3
• Page Start: 659
• Page End: 659
• Publication Date: 2014-01-23
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2012-eular.375
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Women with chronic inflammatory diseases increasingly solicit assisted reproductive techniques (ART) due to infertility, but there is little information about success rates of these techniques in such patients. Objectives: To analyze pregnancy rates after artificial insemination (AI) and in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) in patients with inflammatory rheumatic disease. Methods: Patients: 17 women with inflammatory rheumatic disease: 6 rheumatoid arthritis, 2 spondyloarthritis, 8 systemic lupus erythematosus and 1 Behcet disease, monitored by our department.Mean age 33 years (range 24-40) and 6±2 years from diagnosis of disease, currently inactive or with low clinical activity.Due to infertility, these patients underwent ART: 7 with AI and 9 with IVF-ICSI. Method: We analyzed success rates of both techniques according to patient age, one of the factors that most influence outcome. Results: Pregnancy rate per cycle of AI was 12% with a cumulative rate of 32% after four cycles.In patients over 35 years the pregnancy rate per cycle was reduced to 6%. The pregnancy rate per attempt using IVF-ICSI was 21% with a cumulative rate of 34% after three attempts. In women over 35 years the success rate was 19%. Conclusions: The pregnancy rates of both AI and IVF-ICSI were lower in this series of patients with inflammatory rheumatic disease than those reported for the general population. Disclosure of Interest: None Declared