ZnO Catalyzed Efficient Synthesis of Some New 2-Substituted-4, 6-diarylpyrimidines. (30th October 2012)

• Record Type: Journal Article
• Authors: Ameta, K. L.; Kumar, Biresh; Rathore, Nitu S.
• Other Names: Gattuso G. Academic Editor.; Ishihara J. Academic Editor.; Jios J. L. Academic Editor.; Praly J.-P. Academic Editor.
• Is Part Of: ISRN organic chemistry. Volume 2012(2012)
• Publication Date: 2012-10-30
• Subjects: Chemistry, Organic -- Periodicals; Organic Chemistry Phenomena; Chemistry, Organic; Chemistry, Organic; Periodical; Periodicals; Electronic journals; Fulltext; Internet Resources; Periodicals; 547
• DOI: 10.5402/2012/242569
• Languages: English
• ISSNs: 2090-5149

Abstract

Abstract : A simple and efficient protocol is developed for the synthesis of 2-substituted-4, 6-diarylpyrimidines from one-pot three-component reaction of 4′-hydroxy-3′, 5′-dinitro substituted chalcones, S-benzylthiouronium chloride (SBT), and heterocyclic secondary amines (morpholine/pyrrolidine/piperidine) in the presence of 15 mol% of ZnO as a heterogeneous catalyst. The present methodology offers several advantages such as being a simple procedure as well as providing excellent yields, and short reaction time. The catalyst is inexpensive, stable, and can be easily recycled and reused for several cycles with consistent activity.