Cushing's Syndrome in Childhood: Postoperative Management. Issue 254 (August 1972)

• Record Type: Journal Article
• Authors: Raiti, S.; Grant, D. B.; Williams, D. Innes; Newns, G. H.
• Is Part Of: Archives of disease in childhood. Volume 47:Issue 254(1972)
• Page Start: 597
• Page End: 601
• Publication Date: 1972-08
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.47.254.597
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Of 8 children with Cushing's syndrome, 7 had tumours and 1 bilateral adrenal hyperplasia. All had hypertension; 5 cases also showed virilization; only 3 had short stature. All excreted raised urinary 17KS and 17OHCS. Pyelography showed displaced kidneys on the affected side in 5 cases. Early postoperative complications occurred in 4 cases. 2 patients developed adrenal crisis. In 1 patient the blood pressure rose to very high levels but subsequently fell to normal. The fourth patient developed severe hypertension and acute pancreatitis and died. One patient died from pneumonia 3½ years after operation. A scheme for postoperative replacement therapy with cortisol is given.