Acute encephalopathy with parvovirus B19 infection in sickle cell disease. Issue 6 (1st December 2002)

• Record Type: Journal Article
• Authors: Bakhshi, S; Sarnaik, S A; Becker, C; Shurney, W W; Nigro, M; Savaşan, S
• Is Part Of: Archives of disease in childhood. Volume 87:Issue 6(2002)
• Page Start: 541
• Page End: 542
• Publication Date: 2002-12-01
• Subjects: parvovirus -- vasculitis -- sickle cell disease -- encephalopathy; CNS, central nervous system -- CSF, cerebrospinal fluid -- EEG, electroencephalogram -- MRI, magnetic resonance imaging -- PB19, parvovirus B19 -- PCR, polymerase chain reaction -- RBC, red blood cell -- SCD, sickle cell disease -- WBC, white blood cell; Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.87.6.541
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A 13 year old girl with haemoglobin Sβ + thalassaemia developed simultaneous aplastic crisis and encephalopathy associated with parvovirus B19 (PB19) infection. Brain magnetic resonance imaging findings were consistent with central nervous system (CNS) vasculitis and her symptoms resolved with steroid therapy. Thus, PB19 induced CNS hypersensitivity vasculitis must be considered in the differential diagnosis of encephalopathy.