CD40 ligand deficiency presenting as unresponsive neutropenia. Issue 5 (May 1996)

• Record Type: Journal Article
• Authors: Andrews, F J; Katz, F; Jones, A; Smith, S; Finn, A
• Is Part Of: Archives of disease in childhood. Volume 74:Issue 5(1996)
• Page Start: 458
• Page End: 459
• Publication Date: 1996-05
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.74.5.458
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A male child presented with recurrent respiratory infections, otitis media, and oral ulceration and was found to be neutropenic. Investigations showed hypogammaglobulinaemia with normal serum IgM and a novel deletion in the gene for CD40 ligand on his X chromosome. Intravenous gammaglobulin did not lead to resolution of his neutropenia; G-CSF was also necessary.