Long term neurological dysfunction and neonatal hypoglycaemia after diabetic pregnancy. Issue 3 (1st November 1998)

• Record Type: Journal Article
• Authors: Stenninger, E; Flink, R; Eriksson, B; Sahlèn, C
• Is Part Of: Archives of disease in childhood. Volume 79:Issue 3(1998)
• Page Start: F174
• Page End: F179
• Publication Date: 1998-11-01
• Subjects: hypoglycaemia -- diabetic pregnancy -- neurological development; Infants -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.920105
• DOI: 10.1136/fn.79.3.F174
• Languages: English
• ISSNs: 1359-2998

Abstract

Abstract : AIM: To determine if children born to mothers with diabetes mellitus during pregnancy, who subsequently developed neonatal hypoglycaemia, experienced long term neurological dysfunction. METHODS: Thirteen children with, and 15 without, neonatal hypoglycaemia (blood glucose < 1.5 mmol/l) were randomly selected from a larger cohort and investigated at the age of 8 years. They were also compared with 28 age matched healthy controls. RESULTS: Children with neonatal hypoglycaemia had significantly more difficulties in a validated screening test for minimal brain dysfunction than controls and were also more often reported to be hyperactive, impulsive, and easily distracted. On psychological assessment, they had a lower total development score than normoglycaemic children born to diabetic mothers, and control children. CONCLUSIONS: Neonatal hypoglycaemia in diabetic pregnancy was associated with long term neurological dysfunction related to minimal brain dysfunction/deficits in attention, motor control, and perception.