Gonadal infiltration in children with leukaemia and lymphoma. Issue 8 (August 1980)

• Record Type: Journal Article
• Authors: Reid, H; Marsden, H B
• Is Part Of: Journal of clinical pathology. Volume 33:Issue 8(1980)
• Page Start: 722
• Page End: 729
• Publication Date: 1980-08
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.33.8.722
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : In a postmortem survey of children with leukaemia and lymphoma, the overall incidence of testicular infiltration was 65% and of ovarian infiltration 66%. In acute lymphoblastic leukaemia, testicular infiltration was found in 25 of 39 cases and ovarian infiltration in 6 of 12 cases. The majority of boys with acute lymphoblastic leukaemia and testicular infiltration also had infiltration in other organs; furthermore, in most cases without testicular infiltration leukaemic infiltration was found in other organs. The findings of this survey support the view that testicular infiltration is indicative of widespread disease.