Assessment of a rapid liquid-based cytology method for measuring sputum cell counts. Issue 12 (8th August 2016)

• Record Type: Journal Article
• Authors: Martin, M J; Lee, H; Meakin, G; Green, A; Simms, R L; Reynolds, C; Winters, S; Shaw, D E; Soomro, I; Harrison, T W
• Is Part Of: Thorax. Volume 71:Issue 12(2016)
• Page Start: 1163
• Page End: 1164
• Publication Date: 2016-08-08
• Subjects: Asthma -- Histology/Cytology; Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thoraxjnl-2016-208817
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained using LBC were a strong predictor of sputum eosinophilia (≥3%) determined by the standard method suggesting LBC could be used in the management of asthma.