Outcome of mother to infant acquired GBV-C/HGV infection. Issue 1 (1st January 1999)

• Record Type: Journal Article
• Authors: Zuin, G; Saccani, B; Di Giacomo, S; Tanzi, E; Zanetti, A R; Principi, N
• Is Part Of: Archives of disease in childhood. Volume 80:Issue 1(1999)
• Page Start: F72
• Page End: F73
• Publication Date: 1999-01-01
• Subjects: hepatitis virus infection -- mother to infant transmission -- HIV; Infants -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.920105
• DOI: 10.1136/fn.80.1.F72
• Languages: English
• ISSNs: 1359-2998

Abstract

Abstract : Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV-C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV-C/HGV and hepatitis C virus and HIV coinfection.