Mesoblastic nephroma contains fibronectin but lacks laminin. Issue 5 (May 1985)

• Record Type: Journal Article
• Authors: Kumar, S; Marsden, H B; Carr, T; Kodet, R
• Is Part Of: Journal of clinical pathology. Volume 38:Issue 5(1985)
• Page Start: 507
• Page End: 511
• Publication Date: 1985-05
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.38.5.507
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Non-metastatic mesoblastic nephromas from four young children were shown to contain fibronectin but not laminin using an immunoperoxidase staining procedure. In contrast, one metastasising spindle celled sarcomatous tumour from a neonate was laminin positive. During embryogenesis primitive nephrogenic mesenchyme contains only fibronectin and no laminin; metanephric blastema (permanent kidney) is positive for laminin. The staining for fibronectin and laminin may help to ascertain the histogenesis of different types of renal tumour.