Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey. Issue 2 (15th February 2018)

• Record Type: Journal Article
• Authors: Chen, Liang; Zhou, Fei; Li, Hui; Xing, Xiqian; Han, Xiudi; Wang, Yiming; Zhang, Chunxiao; Suo, Lijun; Wang, Jingxiang; Yu, Guohua; Wang, Guangqiang; Yao, Xuexin; Yu, Hongxia; Wang, Lei; Liu, Meng; Xue, Chunxue; Liu, Bo; Zhu, Xiaoli; Li, Yanli; Xiao, Ying; Cui, Xiaojing; Li, Lijuan; Uyeki, Timothy M; Wang, Chen; Cao, Bin
• Is Part Of: BMJ open. Volume 8:Issue 2(2018)
• Publication Date: 2018-02-15
• Subjects: disease characteristics -- management -- community-acquired pneumonia -- China; Medicine -- Research -- Periodicals; 610.72
• DOI: 10.1136/bmjopen-2017-018709
• Languages: English
• ISSNs: 2044-6055

Abstract

Abstract : Objectives: To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design: This was a multicentre, retrospective, observational study. Setting: 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants: Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures: Resource use for CAP management. Results: Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions: These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number: NCT02489578 ; Results.