Changes produced in the urothelium by traditional and newer therapeutic procedures for bladder cancer. Issue 9 (1st September 2002)

• Record Type: Journal Article
• Authors: Lopez-Beltran, A; Luque, R J; Mazzucchelli, R; Scarpelli, M; Montironi, R
• Is Part Of: Journal of clinical pathology. Volume 55:Issue 9(2002)
• Page Start: 641
• Page End: 647
• Publication Date: 2002-09-01
• Subjects: bladder cancer -- chemotherapy -- immunotherapy -- radiotherapy -- gene therapy; BCG, Bacillus Calmette-Guérin -- CIS, carcinoma in situ -- IFN, interferon -- IL, interleukin -- TURB, transurethral resection of the bladder; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.55.9.641
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A handful of traditional and newer therapeutic procedures, such as chemotherapy, immunotherapy, radiotherapy, photodynamic and laser treatment, and gene therapy, are used to treat epithelial malignancies of bladder origin. These treatment modalities, used either intravesically or systemically, produce morphological changes in the urothelial mucosa that can be mistaken for carcinoma. The pathologist must be able to separate toxic and drug related alterations from tumour related changes. The clinical history is usually invaluable in this assessment.