Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units. Issue 12 (8th March 2018)

• Record Type: Journal Article
• Authors: Bas, Ahmet Yagmur; Demirel, Nihal; Koc, Esin; Ulubas Isik, Dilek; Hirfanoglu, İbrahim Murat; Tunc, Turan
• Other Names: author non-byline.; Sari Fatma Nur author non-byline.; Karatekin Guner author non-byline.; Koklu Esad author non-byline.; Altunhan Huseyin author non-byline.; Turgut Hatice author non-byline.; Narter Fatma author non-byline.; Tarakci Nuriye author non-byline.; Tekgunduz Kadir Serafettin author non-byline.; Ozkiraz Servet author non-byline.; Aydemir Cumhur author non-byline.; Ozdemir Ahmet author non-byline.; Cetinkaya Bilin author non-byline.; Kazanci Ebru author non-byline.; Tastekin Ayhan author non-byline.; Calkavur Sebnem author non-byline.; Ozyurt Banu Mutlu author non-byline.; Demirelli Yaşar author non-byline.; Asker Huseyin Selim author non-byline.; Mutlu Birgul author non-byline.; Uygur Ozgun author non-byline.; Ozkan Hilal author non-byline.; Armangil Didem author non-byline.; Ozlu Ferda author non-byline.; Mert Mustafa Kurthan author non-byline.; Ergin Hacer author non-byline.; Ozcan Beyza author non-byline.; Bas Evrim Kıray author non-byline.; Okulu Emel author non-byline.; Acunas Betul author non-byline.; Celik Ulker author non-byline.; Uslu Sait Ilker author non-byline.; Mutlu Mehmet author non-byline.; Demir Nihat author non-byline.; Eroglu Funda author non-byline.; Gökmen Zeynel author non-byline.; Beken Serdar author non-byline.; Bayraktar Bilge Tanyeri author non-byline.; Hakan Nilay author non-byline.; Kucuktascı Kazım author non-byline.; Orman Aysen author non-byline.; Comert Serdar author non-byline.; Ertugrul Sabahattin author non-byline.; Ustun Nuran author non-byline.; Sahin Ozlem author non-byline.; Terek Demet author non-byline.; Kale Yusuf author non-byline.; Konak Murat author non-byline.; Yurttutan Sadık author non-byline.; Aydemir Ozge author non-byline.; Zenciroglu Ayşegül author non-byline.; Sarici Dilek author non-byline.; Guzoglu Nilufer author non-byline.; Hamilcikan Sahin author non-byline.; Gursoy Tugba author non-byline.; Tuzun Funda author non-byline.; Ors Rahmi author non-byline.; Arslan Selda author non-byline.; Akdag Arzu author non-byline.; Memisoglu Asli author non-byline.; Yasa Beril author non-byline.; Hekimoglu Berna author non-byline.; Turan Ozden author non-byline.; Aylanc Hakan author non-byline.; Takci Sahin author non-byline.; Celik Tolga author non-byline.; Sahin Suzan author non-byline.; Kilic Ilknur author non-byline.; Kara Caner author non-byline.; Tunay Zuhal Ozen author non-byline.; Celik Gokhan author non-byline.; Gozen Ibrahim author non-byline.; Satirtav Gunhal author non-byline.; Polat Nihat author non-byline.; Oral Ayse Yesim author non-byline.; Tokgoz Mine author non-byline.; Keles Sadullah author non-byline.; Bilgin Burak author non-byline.; Ugurbas Silay Canturk author non-byline.; Karaca Cagatay author non-byline.; Keskek Nedime Sahinoglu author non-byline.; Ekinci Dilbade Yildiz author non-byline.; Balci Ozlem author non-byline.; Altan Emir Volkan author non-byline.; Bakbak Sevda author non-byline.; Ceylan Nihan Aksu author non-byline.; Kimyon Sabit author non-byline.; Alyamac Gunay author non-byline.; Ture Gamze author non-byline.; Yildiz Meral author non-byline.; Calis Feyza author non-byline.; Sizmaz Selcuk author non-byline.; Sukgen Emine author non-byline.; Cetin Ebru Nevin author non-byline.; Ozcimen Muammer author non-byline.; Demir Semra Tiryaki author non-byline.; Atila Huban author non-byline.; Ozal Altan author non-byline.; Tufaner Gokhan author non-byline.; Yucel Ozlem Eski author non-byline.; Kola Mehmet author non-byline.; Seven Erbil author non-byline.; Ozdek Sengul author non-byline.; Durukan Ali Hakan author non-byline.; Kal Ali author non-byline.; Cenk Celebi Ali Riza author non-byline.; Koytak Ibrahim Arif author non-byline.; Alacamlı Goksu author non-byline.; Esme Arif author non-byline.; Catak Onur author non-byline.; Perente Irfan author non-byline.; Sahin Alparslan author non-byline.; Akcakaya Aylin Ardagil author non-byline.; Kiray Gulunay author non-byline.; Nalcaci Serhat author non-byline.; Aksoy Umit author non-byline.; Bakbak Berker author non-byline.; Comez Aysegül author non-byline.; Gursoy Huseyin author non-byline.; Kabatas Emrah Utku author non-byline.; Petricli Ikbal Seza author non-byline.; Yumusak Mehmet Erhan author non-byline.; Kirgiz Ahmet author non-byline.; Uludag Gunay author non-byline.; Yaman Aylin author non-byline.; Dadaci Zeynep author non-byline.; Karatas Ali author non-byline.; Celiker Hande author non-byline.; Cebeci Zafer author non-byline.; Esenulku Mahmut Cenap author non-byline.; Akkoyun Imren author non-byline.; Ersan İsmail author non-byline.; Demir Selim author non-byline.; Kadayifcilar Sibel author non-byline.; Akyuz Unsal Ayse Ipek author non-byline.; Hocaoglu Mumin author non-byline.;
• Is Part Of: British journal of ophthalmology. Volume 102:Issue 12(2018)
• Page Start: 1711
• Page End: 1716
• Publication Date: 2018-03-08
• Subjects: Retina -- Child Health (paediatrics) -- Treatment Medical -- Neovascularisation; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjophthalmol-2017-311789
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Background: To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition. Methods: A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)≤1500 g or gestational age (GA)≤32 weeks and those with a BW>1500 g or GA>32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses. Results: The TR-ROP study included 6115 infants: 4964 (81%) with a GA≤32 weeks and 1151 (19%) with a GA>32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW≤1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW≤1500 g. Sixty-six (16%) of the treated infants did not fulfil the Early Treatment for Retinopathy of Prematurity requirements for treatment. Conclusions: Screening of infants with a GA≤34 weeks or a BW<1700 g appears to be appropriate in Turkey. Monitoring standards of neonatal care and conducting quality improvement projects across the country are recommended to improve neonatal outcomes in Turkish NICUs. Trial registration number: NCT02814929, Results.