Beta-thromboglobulin and platelet factor 4 levels in retinal vein occlusion. Issue 3 (March 1983)

• Record Type: Journal Article
• Authors: Dodson, P M; Westwick, J; Marks, G; Kakkar, V V; Galton, D J
• Is Part Of: British journal of ophthalmology. Volume 67:Issue 3(1983)
• Page Start: 143
• Page End: 146
• Publication Date: 1983-03
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.67.3.143
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Fifty-six patients with retinal vein occlusion--35 with central and 21 with branch vein occlusion--were investigated for comparison with an age and sex matched control group. Mean levels of beta-thromboglobulin and platelet factor 4 were significantly higher (p less than 0.001) in both the group with central and the group with branch retinal vein occlusion than in the control group. A significant increase of beta-thromboglobulin (p less than 0.001) was also found in the retinal vein occlusion group in those patients who were not hyperlipidaemic or diabetic (n = 39). Weak correlations were found between levels of lipoprotein cholesterol and plasma beta-thromboglobulin. Increased platelet aggregation may contribute to the aetiology of retinal vein occlusion.