Secondary retinitis pigmentosa and cerebral demyelination in Lyme borreliosis. Issue 2 (February 1993)

• Record Type: Journal Article
• Authors: Karma, A; Pirttilä, T A; Viljanen, M K; Lähde, Y E; Raitta, C M
• Is Part Of: British journal of ophthalmology. Volume 77:Issue 2(1993)
• Page Start: 120
• Page End: 122
• Publication Date: 1993-02
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.77.2.120
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : A 15-year-old girl developed retinitis pigmentosa-like fundus changes in the left eye and optic neuropathy in the right eye as well as cerebral demyelination as a result of late Lyme borreliosis (LB). The diagnosis was confirmed by polymerase chain reaction, which detected a Borrelia burgdorferi specific segment of a gene coding for 41 kD endoflagellin, both in the vitreous and the cerebrospinal fluid. The diagnosis was delayed because testing for Borrelia antibodies in serum and cerebrospinal fluid yielded negative results. However, later on, another laboratory reported the antibodies of the patient's pretreatment serum to be positive for LB.