Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases. Issue 7 (July 1996)

• Record Type: Journal Article
• Authors: Buchanan, N M; Toubi, E; Khamashta, M A; Lima, F; Kerslake, S; Hughes, G R
• Is Part Of: Annals of the rheumatic diseases. Volume 55:Issue 7(1996)
• Page Start: 486
• Page End: 488
• Publication Date: 1996-07
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.55.7.486
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : OBJECTIVE: To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS: The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome. RESULTS: HCQ was not apparently teratogenic. Lupus activity and obstetric outcome in the two groups were similar. CONCLUSION: HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.