A Corrole‐Based Covalent Organic Framework Featuring Desymmetrized Topology. Issue 11 (3rd February 2020)

• Record Type: Journal Article
• Authors: Zhao, Yanming; Dai, Wenhao; Peng, Yunlei; Niu, Zheng; Sun, Qi; Shan, Chuan; Yang, Hui; Verma, Gaurav; Wojtas, Lukasz; Yuan, Daqiang; Zhang, Zhenjie; Dong, Haifeng; Zhang, Xueji; Zhang, Bao; Feng, Yaqing; Ma, Shengqian
• Is Part Of: Angewandte Chemie international edition. Volume 59:Issue 11(2020)
• Page Start: 4354
• Page End: 4359
• Publication Date: 2020-02-03
• Subjects: corrole -- covalent organic framework -- desymmetrized topology -- singlet oxygen; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201915569
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: Herein, for the first time, we present the successful synthesis of a novel two‐dimensional corrole‐based covalent organic framework (COF) by reacting the unusual approximately T‐shaped 5, 10, 15‐tris( p ‐aminophenyl)corrole H3 TPAPC with terephthalaldehyde, which adopts desymmetrized hcb topology and consists of a staggered AB stacking structure with elliptical pores. The resultant corrole‐based COF, TPAPC‐COF, exhibits high crystallinity and excellent chemical stability. The combination of extended π‐conjugated backbone and interlayer noncovalent π–π interactions endows TPAPC‐COF with excellent absorption capability in the entire visible‐light and even near‐infrared regions. Moreover, this work suggests the promise of TPAPC‐COF as a new class of photoactive material for efficient singlet‐oxygen generation with potential photodynamic therapy application as demonstrated by in vitro anticancer studies. Abstract : Tweaking a COF : A novel 2D corrole‐based covalent organic framework (COF) featuring desymmetrized topology has been constructed. Interestingly, this corrole‐COF exhibits a remarkable light‐harvesting capability in the long‐wavelength‐ visible and NIR regions, serves as a promising photoactive material for generating singlet oxygen, and displays excellent anticancer efficacy.