A cooperative zinc/catalytic indium system for the stereoselective sequential synthesis of (E)-1, 3-dienes from carbonyl compounds. Issue 3 (14th December 2020)

• Record Type: Journal Article
• Authors: González-Rodríguez, Jorge; Soengas, Raquel G.; Rodríguez-Solla, Humberto
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 3(2021)
• Page Start: 591
• Page End: 598
• Publication Date: 2020-12-14
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d0qo01388a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A novel cooperative system based on zinc/catalytic indium for the stereoselective synthesis of highly functionalized ( E )-1, 3-dienes from aldehydes and ketones has been developed. Abstract : Herein we describe a cooperative zinc/indium system for the stereoselective synthesis of highly functionalized ( E )-1, 3-dienes through the sequential allylation/elimination reaction of aldehydes and ketones with 1, 3-dichloropropene. The main advantages of this methodology are that it has a broad substrate scope and simple procedure, requires mild conditions and is easy to operate.