Drug Delivery: Activated Platelets‐Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer (Adv. Funct. Mater. 13/2019). (26th March 2019)

• Record Type: Journal Article
• Authors: Zhang, Yujie; Zhu, Xi; Chen, Xinli; Chen, Qinjun; Zhou, Wenxi; Guo, Qin; Lu, Yifei; Li, Chao; Zhang, Yu; Liang, Donghui; Sun, Tao; Wei, Xunbin; Jiang, Chen
• Is Part Of: Advanced functional materials. Volume 29:Number 13(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-03-26
• Subjects: activated platelets -- circulating tumor cells -- metastasis -- micelles -- P‐selectin; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970086
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number 1806620, Chen Jiang and co‐workers, inspired by the ability of activated platelets to track tumor metastasis, develop a novel activated plateletstargeting micelle for efficient anticancer drug delivery to primary and metastatic tumors. After specifically binding to activated platelets in circulation, the micelles capture circulating tumor cells (CTCs) through the "platelet bridge" and eliminate CTCs to prevent metastasis.