Diaphragm strength in acute systemic lupus erythematosus in a patient with paradoxical abdominal motion and reduced lung volumes. Issue 4 (1st April 2001)

• Record Type: Journal Article
• Authors: Hawkins, P; Davison, A G; Dasgupta, B; Moxham, J
• Is Part Of: Thorax. Volume 56:Issue 4(2001)
• Page Start: 329
• Page End: 330
• Publication Date: 2001-04-01
• Subjects: systemic lupus erythematosus -- diaphragmatic strength -- lung volumes; Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thorax.56.4.329
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Diaphragmatic weakness is reported as a common feature of the shrinking lung syndrome of systemic lupus erythematosus (SLE). However, in chronic stable SLE it has been shown that, despite poor performance of voluntary tests of diaphragm strength, twitch pressures obtained by stimulating the phrenic nerves are normal. We present a patient with acute SLE and pulmonary involvement who, despite having paradoxical abdominal motion and low maximal inspiratory pressures during voluntary manoeuvres, had normal diaphragm strength when assessed with magnetic stimulation of the phrenic nerves. Following immunosuppressive therapy symptoms and lung function improved, yet diaphragm contractility remained normal and unchanged. We suggest that this case supports the view that reduced diaphragm muscle contractility per se does not explain the small volume lungs and respiratory symptoms in patients with acute SLE.