Biofilm-associated infections: antibiotic resistance and novel therapeutic strategies. (July 2013)

• Record Type: Journal Article
• Authors: Sun, Fengjun; Qu, Feng; Ling, Yan; Mao, Panyong; Xia, Peiyuan; Chen, Huipeng; Zhou, Dongsheng
• Is Part Of: Future microbiology. Volume 8:Number 7(2013:Jul.)
• Page Start: 877
• Page End: 886
• Publication Date: 2013-07
• Subjects: antibiotic resistance -- biofilm -- infection -- treatment; Microbiology -- Research -- Periodicals; 616.9041
• DOI: 10.2217/fmb.13.58
• Languages: English
• ISSNs: 1746-0913

Abstract

Infections with bacterial or fungal biofilms have emerged as a major public heath concern because biofilm-growing cells are highly resistant to both antibiotics and host immune defenses. This review focuses on the progress in understanding the mechanisms of biofilm-specific antimicrobial resistance and in developing innovative therapeutic measures based on novel antibiofilm agents.