Should intramuscular clozapine be adopted into mainstream clinical practice?. (July 2021)

• Record Type: Journal Article
• Authors: Bhattacherjee, Shaun; Young, Anthony; Ahuja, Niraj; Allen, Steven
• Is Part Of: British journal of psychiatry. Volume 219:Number 1(2021)
• Page Start: 357
• Page End: 358
• Publication Date: 2021-07
• Subjects: Antipsychotics -- schizophrenia -- in-patient treatment -- outcome studies -- psychotic disorders; Psychiatry -- Periodicals; Psychology, Pathological -- Periodicals; 616.89005
• DOI: 10.1192/bjp.2021.36
• Languages: English
• ISSNs: 0007-1250

Abstract

Summary: Clozapine is under-used in the UK, and Casetta et al's recent paper in the BJPsych adds to a growing number of small studies that support the use of intramuscular clozapine to initiate and maintain treatment with oral clozapine. However, intramuscular clozapine remains unlicensed and, because of the risks associated with its administration, it should be used only cautiously before it can be adopted more widely into mainstream clinical practice.